Elevated plasma ICAM1 levels predict 28-day mortality in cirrhotic patients with COVID-19 or bacterial sepsis
نویسندگان
چکیده
منابع مشابه
Admission Cell Free DNA Levels Predict 28-Day Mortality in Patients with Severe Sepsis in Intensive Care
AIM The aim of the current study is to assess the mortality prediction accuracy of circulating cell-free DNA (CFD) level at admission measured by a new simplified method. MATERIALS AND METHODS CFD levels were measured by a direct fluorescence assay in severe sepsis patients on intensive care unit (ICU) admission. In-hospital and/or twenty eight day all-cause mortality was the primary outcome....
متن کاملDevelopment and validation of immune dysfunction score to predict 28-day mortality of sepsis patients
BACKGROUND Sepsis-induced immune dysfunction ranging from cytokines storm to immunoparalysis impacts outcomes. Monitoring immune dysfunction enables better risk stratification and mortality prediction and is mandatory before widely application of immunoadjuvant therapies. We aimed to develop and validate a scoring system according to patients' immune dysfunction status for 28-day mortality pred...
متن کاملLevels of circulating miR-133a are elevated in sepsis and predict mortality in critically ill patients.
OBJECTIVE Serum levels of microRNA have been proposed as biomarkers in various inflammatory diseases. However, up to now, their clinical relevance in critical illness and sepsis is unclear. DESIGN Single-center clinical study. SETTING Fourteen-bed medical ICU of the University Hospital Aachen, university laboratory research unit. SUBJECTS AND PATIENTS Experimental sepsis model in C57Bl/6 ...
متن کاملSequential changes in plasma cytokine and endotoxin levels in cirrhotic patients with bacterial infection.
To delineate the clinical roles of plasma cytokine or endotoxin levels in the natural course of infection in patients with decompensated cirrhosis, 66 cirrhotic patients were studied within a 1.5-year period. Plasma levels of tumour necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), IL-6, IL-8 and endotoxin were determined on days 1, 4 and 7 after admission when hospital infection...
متن کاملCan heparin therapy reduce 28-day mortality in adult severe sepsis patients?
A study by Wang and colleagues [1] in a previous issue of Critical Care shows that heparin may reduce 28-day mortality in severe sepsis patients without causing an increased risk of bleeding. Therefore, the authors recommend the use of heparin for sepsis and severe sepsis. Although their result may significantly influence clinical practice, several confounding factors should be noticed. In this...
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ژورنال
عنوان ژورنال: JHEP Reports
سال: 2021
ISSN: 2589-5559
DOI: 10.1016/j.jhepr.2021.100303